Model of convergent extension in animal morphogenesis.
نویسندگان
چکیده
We argue that energy minimization can explain the pattern of cell movements in the morphogenetic process known as convergent extension provided that the cell-cell adhesive energy has a certain type of anisotropy, which we describe. This single simple property suffices to cause the cell elongation, cell alignment, and lengthening of a cellular array that characterize convergent extension. We show that the final aspect ratio of the array of cells depends on the anisotropy and is independent of the initial configuration and of the degree of cell elongation.
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عنوان ژورنال:
- Physical review letters
دوره 85 9 شماره
صفحات -
تاریخ انتشار 2000